Reversing Neuropathy

There are many side effects from the disease of diabetes but the most debilitating is the pain that is associated with diabetic neuropathy. Several DAMPs have been implicated in neuropathic pain, including High Mobility Group Box 1 (HMGB1), Heat shock proteins (HSP)-60 and -90, biglycan and fibrinogen 34. These molecules are typically sequestered within intracellular compartments or the extracellular matrix, and become liberated into the extracellular milieu during stress or damage.
Degenerative changes in the cervical vertebrae and surrounding soft tissues (ligaments, intervertebral discs, joint capsules) cause narrowing of the spinal canal where the spinal cord itself passes, as well as the openings that allow passage of nerve roots as they exit the spinal cord and travel to other parts of the body.



As early as 1997, Abuaisha et al of the Department of Medicine, Manchester Royal Infirmary conducted a study entitled, "Acupuncture for the treatment of chronic peripheral diabetic neuropathy: a long-term study." It studied the effectiveness of acupuncture in alleviating the painful symptoms of diabetic peripheral neuropathy.
Just like with diabetes itself, there is no known cure” for peripheral neuropathy, only ways to manage it and stop progression, similarly to the natural treatments for diabetes It's a dangerous problem to have, but fortunately most people are able to keep it under control by regulating their blood sugar levels, changing their diets and adopting healthier lifestyles overall, all of which help control their diabetes.

In addition, there are other neurotrophic factors, such as insulinlike growth factor (IGF) and glial-derived neurotrophic factor 27 Present studies suggest that diabetes-induced dysfunction of nerve regeneration results partially from decreased levels of some neurotrophic factors or their receptors.
As the location of the first synapse of primary corneal afferents that transmit noxious corneal sensations, the homeostatic corneal surface wetness control centre and the centre for monitoring the averseness of ambient light levels the trigeminal brainstem would appear to be the location of the neuropathic disease capable of causing trigeminal-projected pain and otherwise unexplained photophobia.
This concerted action of neuronal and non-neuronal cells in peripheral tissues constitutes a form of inflammation that is triggered by neuronal activity and is thus labeled neurogenic inflammation (Chiu, von Hehn, & Woolf, 2012 ). Some of the pro-inflammatory substances released in the course of a neurogenic inflammation directly excite or sensitize nociceptive nerve endings and thus constitute a peripheral generator or amplifier for pain.

In the Steno type 2 randomized study, improved glycemic control in type 2 diabetes was associated with a lower rate of progression of autonomic neuropathy 17 In this study, intensive Reverse Neuropathy Pain treatment was a stepwise implementation of behavior modification and pharmacologic therapy targeting hyperglycemia, hypertension, dyslipidemia, and microalbuminuria.
While there are many opinions and research findings, my clinical experience of being a pain psychologist for the past 15 years, coupled with brain science, I have found a three prong approach works best: (1) Knowledge shift (Pain in the Brain); (2) Emotional Regulation (I help my patients with ACT - not having them control or change their thinking about their pain); and (3) Mindful Based Movements (Tai Chi, Yoga, Qi Gong, total body conditioning).